The Argentina international is on 499 senior career goals and is keen to reach a milestone against his teams rivals when the two sides clash on Saturday evening.
Barcelona star Lionel Messi says it would be a special moment to score his 500th career goal in Saturday’s Clasico at Camp Nou.
The 28-year-old struck his 50th international goal from the penalty spot in Argentina’s 2-0 World Cup qualifying victory over Bolivia on Tuesday.
That strike put Messi on 499 in his senior career and the five-time Ballon d’Or winner has set his sights on hitting his next milestone against fierce rivals Real Madrid.
“It would be a nice moment to reach that figure against Real Madrid. It would be nice to win to stretch our advantage,” he told reporters.